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The Journal of Organic Chemistry

Rates of formation of iminium ions from acetone and monoprotonated 2-[(dimethylamino) methyl] pyrrolidine

J Hine, RA Evangelista

文献索引:Hine, Jack; Evangelista, Ramon A. Journal of Organic Chemistry, 1980 , vol. 45, # 19 p. 3890 - 3892

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被引用次数: 2

摘要

Results Lithium aluminum hydride reduction of N, N-di-methyl-5-oxo-2- pyrrolidinecarboxamide gave 1, which has also been prepared by reduction of the N, N- dimethylamide of pr~ line.~ Its thermodynamic pK, values in water at 35" C were found to be 9.82 and 5.77. Equilibrium constants for iminium ion formation from acetone and secondary amines in aqueous solution are so small that it is not practical to follow the reactions ...