Tetrahedron

Synthesis of pyrazino [2, 3-e][1, 4] diazepin-5-one and pyrazino [2, 3-e] pyrrolo [1, 2-a][1, 4] diazepin-5-one derivatives via the intramolecular aza-Wittig reaction

T Okawa, S Eguchi

文献索引：Okawa, Tomohiro; Eguchi, Shoji Tetrahedron, 1998 , vol. 54, # 22 p. 5853 - 5868

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被引用次数: 22

摘要

2-Alkoxy pyrazino [2, 3-e][1, 4] diazepin-5-one and 11-alkoxy pyrazino [2, 3-e] pyrrolo [1, 2- a][1, 4] diazepin-5-one derivatives were synthesized via the corresponding iminophosphoranes derived from 3-aminopyrazine-2-carboxylic acid and α-amino acid derivatives, by the intramolecular aza-Wittig methodology.(11S, 11aS)-1, 2, 3, 10, 11, 11a- Hexahydro-11-alkoxy-pyrazino [2, 3-e] pyrrolo [1, 2-a][1, 4] diazepin-5-one derivatives, ie, ...