Solid phase synthesis and SAR of small molecule agonists for the GPR40 receptor

SC McKeown, DF Corbett, AS Goetz, TR Littleton…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 6 p. 1584 - 1589

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被引用次数: 61

摘要

... Bioorganic & Medicinal Chemistry Letters. Volume 17, Issue 6, 15 March 2007, Pages 1584–1589. ... In addition, 1 was an attractive molecule for chemical optimisation since it can be assembled with relatively simple chemistry allowing for rapid exploration of the SAR. ...