A High??Yield Selective N (3)??Alkylation Process of Hydantoins Using Dimethylformanide Dialkyl Acetals

…, C Smeyers, P Böttcher

文献索引：Poupaert; Smeyers; Bottcher Bulletin des Societes Chimiques Belges, 1985 , vol. 94, # 6 p. 431 - 434

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被引用次数: 5

摘要

Bull. SOC. Chim. Belg. vol. 94/n06/1985 ... A HIGH-YIELD SELECTIVE N(3)-ALKYfATION PROCESS OF HY-INS ... Jacques H. Poupaert, Claude Smeyers, and Patrick Bijttcher, Mpartemnt de Chimie et Technologic Phamaceutiques, UCL ... ABSTRACT A selective N(3)-alkylation process of 5-substituted hydantoins is described. Treatment of hydantoins with excess of dimethylformamide dialkyl acetals at 100°C results in N(3)-alkyl derivatives in 69-90 6 yield.