Abstract Glutamic acid analogs containing 3-and 4-methyl and 2-, 3-, and 4-phenyl substituents were prepared. The 3-and 4-methyl-and 3-and 4-phenylglutamic acids did not inhibit Plasmodium berghei and were nontoxic to the host (mice) at 640 mg/kg. The five analogs in addition to 2-methylglutamic acid were inactive against Lactobacillus casei at 1000 μg/ml in a defined medium; against Escherichia coli, only 2-methylglutamic acid ...
