2, 2′-Bipyridinebutyldithiocarbamatoplatinum (II) and palladium (II) complexes: synthesis, characterization, cytotoxicity, and rich DNA-binding studies

H Mansouri-Torshizi, I Mahboube, A Divsalar…

文献索引：Mansouri-Torshizi, Hassan; I-Moghaddam, Mahboube; Divsalar, Adeleh; Saboury, Ali-Akbar Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 21 p. 9616 - 9625

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被引用次数: 79

摘要

Butyldithiocarbamate sodium salt (Bu-dtcNa) and its two complexes,[M (bpy)(Bu-dtc)] NO3 (M= Pt (II) or Pd (II) and bpy= 2, 2′-bipyridine), have been synthesized and characterized on the basis of elemental analysis, molar conductivities, IR, 1H NMR, and UV–vis spectra. In these complexes, the dithiocarbamato ligand coordinates to Pt (II) or Pd (II) center as bidentate with two sulfur atoms. These complexes show 50% cytotoxic concentration ( ...