Tetrahedron Letters

A short synthesis of (2S, 3S)-3-hydroxypipecolic acid

SP Chavan, KR Harale, KP Pawar

文献索引：Chavan, Subhash P.; Harale, Kishor R.; Pawar, Kailash P. Tetrahedron Letters, 2013 , vol. 54, # 36 p. 4851 - 4853

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被引用次数: 6

摘要

Synthesis of medicinally important scaffolds starting from naturally abundant and cheap chiral materials has been an area of endless interest. The piperidine alkaloids 1 over the years attracted the attention of organic chemists toward their synthesis due to their wide range of biological properties. One of the most important classes of piperidine alkaloids is imino sugar, 2 which exhibits a wide range of bioactivity. One of them, 3-hydroxypipecolic acid (1), 3 is an important ...