Abstract Regioselective mono and dihalogenations of amino, hydroxy and methoxy pyridines (2-, 3-, and 4-substituted) as well as 2, 6-dimethoxy pyridine with N- bromosuccinimide in different solvents have been studied. Reactivity of the substrates decreases in the order amino> hydroxy> methoxy and regioselectivity depends on the position of the substituent (2-substituted> 3-substituted). In most of the cases we obtained ...