Discovery of new orally active phosphodiesterase (PDE4) inhibitors

H Ochiai, A Ishida, T Ohtani, K Kusumi…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 52, # 9 p. 1098 - 1104

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被引用次数: 15

摘要

... Chemistry The synthesis of the test compounds listed in Tables 1—3 is outlined in ... Shimamoto, Mishima, Osaka 618–8585, Japan: and b Development Planning, Ono Pharmaceutical Co., Ltd.; 2 ... Chemical modification of 3, a structurally new chemical lead that was found in our in ...