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Complete conversion of L-lactate into D-lactate. A generic approach involving enzymic catalysis, electrochemical oxidation of NADH and electrochemical reduction of …

…, C Bourdillon, JM Laval, G Mairesse…

文献索引:Biade, Azz-Eddine; Bourdillon, Christian; Laval, Jean-Marc; Mairesse, Gilles; Moiroux, Jacques Journal of the American Chemical Society, 1992 , vol. 114, # 3 p. 893 - 897

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被引用次数: 57

摘要

Abstract: L-Lactate was converted into D-lactate with a yield better than 97%, the system involving stereospecific catalysis of L-lactate oxidation by the rather cheap L-lactate dehydrogenase plus electrochemical regeneration of NAD+ at the anode and electrochemical reduction of pyruvate at the cathode. Such an approach can be extended to mere deracemization or complete inversion of all types of chiral a-alcoholacids provided ...