Synthesis of ethyl 6??aryl??4??oxo??4, 6??dihydro??1 (12)(13) h??pyrimido??[2′, 1′: 4, 5][1, 3, 5] triazino [1, 2??a] benzimidazole??3??carboxylates

AV Dolzhenko, WK Chui…

文献索引：Dolzhenko, Anton V.; Chui, Wai-Keung; Dolzhenko, Anna V. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1513 - 1521

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被引用次数: 14

摘要

The synthesis of ethyl 6-aryl-4-oxo-4, 6-dihydro-1 (12)(13) H-pyrimido [2', 1': 4, 5][1, 3, 5] triazino [1, 2-a]-benzimidazole-3-carboxylates (4a-p) was described via pyrimidine ring annulation to 4-aryl-3, 4-dihydro [1, 3, 5] triazino [1, 2-a] benzimidazole-2-amines (2a-p) which were obtained from 2-guanidinobenzimidazole (1). Tautomerism in the prepared compounds was investigated using nmr spectroscopy. Compounds 2a-p were found to be ...