Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents

…, A Ćirić, M Soković, I Doytchinova, A Geronikaki

文献索引：Solankee, Anjani; Kapadia, Kishor; Ana Ciric; Sokovic, Marina; Doytchinova, Irini; Geronikaki, Athina European Journal of Medicinal Chemistry, 2010 , vol. 45, # 2 p. 510 - 518

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被引用次数: 80

摘要

Base catalysed condensation of ketone 5 with different aldehydes give chalcones, 2.4-bis- (phenylamino)-6-[4′-{3 ″-(4‴-substituted phenyl/2‴-furanyl/2‴-thienyl)-2 ″-propenon-1 ″-yl} phenylamino]-s-thriazines 6a–e. These chalcones on cyclization with hydrazine hydrate in the presence of glacial acetic acid, guanidine nitrate in the presence of alkali and malononitrile in the presence of ammonium acetate give the corresponding ...