Identification of a pharmacophore for thrombopoietic activity of small, non-peptidyl molecules. 1. Discovery and optimization of salicylaldehyde thiosemicarbazone …

KJ Duffy, AN Shaw, E Delorme, SB Dillon…

文献索引：Journal of Medicinal Chemistry, , vol. 45, # 17 p. 3573 - 3575

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被引用次数: 86

摘要

... Journal of Medicinal Chemistry. ... The application of high-throughput chemistry and purification techniques facilitated the simultaneous synthesis of arrays of salicylaldehyde thiosemicarbazones and allowed for the rapid elucidation of structure−activity relationships. ...