Tetrahedron letters

Practical enantiospecific synthesis of RPR 111905: A novel non-peptide substance P antagonist

S Mutti, C Daubié, J Malpart, X Radisson

文献索引：Mutti, Stephane; Daubie, Christophe; Malpart, Joel; Radisson, Xavier Tetrahedron Letters, 1996 , vol. 37, # 48 p. 8743 - 8746

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被引用次数: 9

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The synthesis of enantiomerically pure RPR 111905 was achieved in twelve steps with an overall yield of 6.9%. The synthetic strategy was based on a Diels-Alder reaction to generate the bicyclic framework and the asymmetry was introduced by resolution.