N-. omega.-Fluoroalkyl Analogs of (1R)-2. beta.-Carbomethoxy-3. beta.-(4-iodophenyl) tropane (. beta.-CIT): Radiotracers for Positron Emission Tomography and …

…, NS Kula, RJ Baldessarini, Y Zea-Ponce…

文献索引：Neumeyer; Wang; Gao; Milius; Kula; Campbell; Baldessarini; Zea-Ponce; Baldwin; Innis Journal of Medicinal Chemistry, 1994 , vol. 37, # 11 p. 1558 - 1561

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被引用次数: 148

摘要

Imaging techniques are increasingly applied to neurochemical and neuropharmacological studies of brain function. PET (positron emission tomography) and SPECT (single photon emission computed tomography) methods can be applied with high sensitivity in such studies. Though spatial resolution remains somewhat greater with PET, several advantages are offered by SPECT technology. Positron-emitting nuclides have short half-lives (eg, ...