4-Functionally Substituted 3-Heterylpyrazoles: III. 3-Aryl (heteryl) pyrazole-4-carboxylic Acids and Their Derivatives

MK Bratenko, VA Chornous, MV Vovk

文献索引：Bratenko; Chornous; Vovk Russian Journal of Organic Chemistry, 2001 , vol. 37, # 4 p. 552 - 555

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被引用次数: 6

摘要

Abstract-3-Aryl(heteryl)-4-formylpyrazoles were cleanly oxidized by potassium permanganate in water- pyridine medium to afford in high yield 3-aryl(heteryl)pyrazole-4-carboxylic acids, that were further converted into the corresponding chlorides and amides. ... In the series of functionally substituted pyrazoles are important 4-pyrazolecarboxylic acids. On their capability to decarboxylate at elevated temperature is based an extensively used preparation method for pyrazoles ...