Departainento de Quimica Orgbnica. Facultad de Ciencias. Universidaa de Valladolid, 47011-Valladolid, Spain. ... Abstract. 2-Acylthiophenes and ethyl Z-thiophene- carboxylates are prepared regioselectively by reaction of 3-chloroenones and 2-acylenammonium chlorides with N - mercaptoderivativesin good tomoderateyields . ... The use of 1,3-Difunctional substrates in the ... 2-thiophenecarboxylic acid derivatives. On the other hand, we have recently ...