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Synthesis of halogen-substituted pyridyl and pyrimidyl derivatives of [3, 2-c] pyrazolo corticosteroids: strategies for the development of glucocorticoid receptor …

RM Hoyte, J Zhang, R Lerum, A Oluyemi…

文献索引:Journal of Medicinal Chemistry, , vol. 45, # 24 p. 5397 - 5405

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被引用次数: 34

摘要

... Journal of Medicinal Chemistry. ... Ligands for the glucocorticoid receptor labeled with high-energy isotopes are highly desired for their potential applications in nuclear medical studies of the brain where the dysregulation of this receptor system is thought to be involved in ...