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Tetrahedron letters

Novel approach to the synthesis of AZT 5′-O-hydrogen phospholipids

Q Xiao, J Sun, Y Ju, Y Zhao, Y Cui

文献索引:Xiao, Qiang; Sun, Jing; Ju, Yong; Zhao, Yu-Fen; Cui, Yu-Xin Tetrahedron Letters, 2002 , vol. 43, # 30 p. 5281 - 5283

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被引用次数: 9

摘要

A series of AZT 5′-O-hydrogen phospholipids were synthesized by a tandem transesterification of diphenyl phosphite with AZT and a long-chain alcohol. The method possesses the merits of ease of operation and high yields. It can also be extended to synthesize other biological phospholipids.