Efficient Synthesis of Sivelestat Sodium Hydrate

G Bijukumar, B Maloyesh, SS Sampat…

文献索引：Bijukumar; Maloyesh; Sampat; Bhirud; Rajendra Synthetic Communications, 2008 , vol. 38, # 11 p. 1718 - 1724

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被引用次数: 2

摘要

View all references in the preparation of antiwrinkle cosmetic composition, which includes sivelestat. The antiwrinkle activity is believed to be the result of effective elastase inhibition, reduced hydrolytic rate, and the increased content of elastin in derma cortex by the elastase inhibitors. ... Sivelestat sodium hydrate is chemically known as N??[2??[4??(pivaloyloxy) phenylsulfonamido] benzoyl] glycine sodium salt tetrahydrate 1 (Fig. 1).