Direct reductive amination of aldehydes using lithium-arene (cat.) as reducing system. A simple one-pot procedure for the synthesis of secondary amines

F Nador, Y Moglie, A Ciolino, A Pierini, V Dorn, M Yus…

文献索引：Nador, Fabiana; Moglie, Yanina; Ciolino, Andres; Pierini, Adriana; Dorn, Viviana; Yus, Miguel; Alonso, Francisco; Radivoy, Gabriel Tetrahedron Letters, 2012 , vol. 53, # 25 p. 3156 - 3160

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被引用次数: 21

摘要

A simple one-pot procedure for the direct reductive amination of aldehydes using lithium powder and a catalytic amount of 4, 4′-di-tert-butylbiphenyl (DTBB) or a polymer supported naphthalene as reducing system is described. The direct reductive amination of a variety of aldehydes with primary amines was achieved simply by adding a mixture of the corresponding carbonyl compound and the amine, over a solution of the lithium arenide in ...