Journal of the American Chemical Society

Mechanism and selectivity in nickel-catalyzed cross-electrophile coupling of aryl halides with alkyl halides

S Biswas, DJ Weix

文献索引：Shrestha, Ruja; Dorn, Stephanie C. M.; Weix, Daniel J. Journal of the American Chemical Society, 2013 , vol. 135, # 2 p. 751 - 762

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被引用次数: 107

摘要

The direct cross-coupling of two different electrophiles, such as an aryl halide with an alkyl halide, offers many advantages over conventional cross-coupling methods that require a carbon nucleophile. Despite its promise as a versatile synthetic strategy, a limited understanding of the mechanism and origin of cross selectivity has hindered progress in reaction development and design. Herein, we shed light on the mechanism for the nickel- ...