Tetrahedron

Synthesis of 6-hydroxy-2-naphthoic acid from 2, 6-diisopropylnaphthalene using NHPI as a key catalyst

R Nakamura, Y Obora, Y Ishii

文献索引：Nakamura, Ryota; Obora, Yasushi; Ishii, Yasutaka Tetrahedron, 2009 , vol. 65, # 18 p. 3577 - 3581

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被引用次数: 10

摘要

A new strategy to 6-hydroxy-2-naphthoic acid (HNPA) and 4-hydroxybenzoic acid from 2, 6- diisopropylnaphthalene and p-cymene, respectively, was developed using the NHPI- catalyzed aerobic oxidation as a principal reaction. 2, 6-Diisopropylnaphthalene was oxidized by the oxidation with O2 (1atm) by NHPI (10mol%) combined with Co (OAc) 2 (0.5 mol%) to give 6-acetyl-2-isopropylnaphthalene, which then was converted to 6-isopropyl- ...