Unique and convenient use of Raney nickel for the reduction of aryl bromides, benzyl alcohols, benzyl ethers, and benzylamines in an acidic medium

M Okimoto, Y Takahashi, Y Nagata, M Satoh…

文献索引：Okimoto, Mitsuhiro; Takahashi, Yukio; Nagata, Yuji; Satoh, Masanori; Sueda, Satoru; Yamashina, Tsunaki Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 7 p. 1405 - 1406

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被引用次数: 7

摘要

A simple and convenient method for laboratory-scale reduction using Raney nickel is described. The reaction was achieved by the inclusion of sulfuric acid to a mixture of a substrate and Raney nickel. Using this method, several aryl bromides, benzyl alcohols, benzyl ethers, and benzylamines were cleaved at the carbon–bromine bond or at the benzylic position to afford corresponding hydrogenated products in good yields without ...