Summary. A facile high-yield synthesis of 7-deazaadenosine(tubercidin, z), 7- deazaguanosine (lo) t 2'-deoxy-7-deaza-6-thioguanosine(12) and 2'-deoxy-7- deazaguanosine(15) by the regioselective and stereospecific sodium salt glycosylation procedure is described.