Organic letters

Investigation of the Yamaguchi esterification mechanism. Synthesis of a Lux-S enzyme inhibitor using an improved esterification method

I Dhimitruka, J SantaLucia

文献索引：Dhimitruka, Ilirian; SantaLucia Jr., John Synlett, 2004 , # 2 p. 335 - 337

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被引用次数: 105

摘要

A one-pot procedure for the regioselective synthesis of aliphatic esters is described. This was a result of a study on mixed aliphatic-aromatic anhydrides. The data suggest that during the Yamaguchi esterification reaction, a symmetric aliphatic anhydride is produced in situ,