Journal of the American Chemical Society

BETA-ARYLAMINO ETHANOLS

R Adams, JB Segur

文献索引：Adams; Segur Journal of the American Chemical Society, 1923 , vol. 45, p. 789

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被引用次数: 13

摘要

The animals used were rabbits and dogs and the drugs were given by mouth. Non-febrile rabbits were first used. The toxicity of phenacetin and the oxazolidone was found to be approximately the same, about 3 g. per kg. of weight. Both caused symptoms which may be referred to the central nervous system. In fatal doses the phenacetin caused depression and paralysis, whereas the oxazolidone caused convulsions or stimulation. In doses which ...