Diastereomeric 6-desoxy-6-spiro-. alpha.-methylene-. gamma.-butyrolactone derivatives of naltrexone and oxymorphone. Selective irreversible inhibition of naltrexone …

GA Koolpe, WL Nelson, TL Gioannini…

文献索引：Journal of Medicinal Chemistry, , vol. 27, # 12 p. 1718 - 1723

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被引用次数: 12

摘要

... t University of Washington. *New York University Medical Center. 0022-262318411827-1718 $01.50/0 Scheme Io HO c l H? HO H? ... deriva- tives 4a and 4b in approximately 60% yield. C P M y g Q 2 on = Journal of Medicinal Chemistry, 1984, Vol. 27, No. 12 1719 ...