Synthesis and Antiviral Bioactivities of 2-Cyano-3-substituted-amino (phenyl) Methylphosphonylacrylates (Acrylamides) Containing Alkoxyethyl Moieties†

…, B Song, PS Bhadury, Z Chen, S Yang…

文献索引：Yang, Jia-Qiang; Song, Bao-An; Bhadury, Pinaki S.; Chen, Zhuo; Yang, Song; Xue-Jian, Cai; Hu, De-Yu; Xue, Wei Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 5 p. 2730 - 2735

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被引用次数: 29

摘要

An efficient reaction under microwave irradiation has been developed for the synthesis of a series of novel 2-cyano-3-substituted-amino (phenyl) methylphosphonylacrylates (acrylamides) II. The products obtained in shorter reaction time with moderate yields are fully characterized by elemental analysis, IR, 1H, 13C, and 31P NMR spectral data. The role of introducing various substituents and the effect of incorporating α-aminophosphonates with ...