Helvetica Chimica Acta

Synthesis, Characterization, and Anti??amoebic Screening of Core??Modified 5, 20??Bis {2??{[(alkyl)(alkyl′) amino] methyl} ferrocen??1??yl}??10, 15??diphenyl??21, 23?? …

AR Bhat, AI Bhat, F Athar, A Azam

文献索引：Bhat, Abdul R.; Bhat, Asif I.; Athar, Fareeda; Azam, Amir Helvetica Chimica Acta, 2009 , vol. 92, # 8 p. 1644 - 1656

全文：HTML全文

被引用次数: 12

摘要

Abstract The synthesis of the first bis-ferrocenyl-substituted core-modified porphyrins, 5, 20- bis {2-{[(alkyl)(alkyl′) amino] methyl} ferrocen-1-yl}-10, 15-diphenyl-21, 23-dithiaporphyrin derivatives 6a–6j, via a multistep route is reported (Schemes 1, 2, and 4). The synthesis was carried out through acid-catalyzed (BF 3⋅ Et 2 O) condensation of 1, 1 ″-[thiophene-2, 5- diylbis (hydroxymethyl)] bis [2-{[(alkyl)(alkyl′) amino] methyl} ferrocenes] 4a–4j with 2, 2 ...