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Synthesis of Novel Coumarin-Based Fluorescent Probes

I Kosiova, P Kois

文献索引:Kosiova, Ivana; Kois, Pavol Collection of Czechoslovak Chemical Communications, 2007 , vol. 72, # 8 p. 996 - 1004

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被引用次数: 5

摘要

Abstract We report on synthesis of new fluorescent probes suitable for site-specific incorporation into oligonucleotides. Coumarin derivatives were used as sensitive fluorescent labels and were attached to glycerol unit by two types of linkers as potential building blocks for oligonucleotide synthesis. Spectral characteristics of the functionalized coumarin building blocks were measured.