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Non-peptidic small molecule inhibitors of XIAP

CM Park, C Sun, ET Olejniczak, AE Wilson…

文献索引:Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 3 p. 771 - 775

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被引用次数: 66

摘要

... Bioorganic & Medicinal Chemistry Letters. ... The resulting compounds were initially assayed by NMR, which is able to confirm binding to the SMAC binding site by the observation of chemical shift pertubations and to quantitate weak binding in the millimolar to micromolar range. ...