前往化源商城

The Journal of Organic Chemistry

Simple preparations of N-(tert-butyloxycarbonyl)-O-methyl-L-serine and N-(tert-butyloxycarbonyl)-O-methyl-L-threonine by direct methylation

FMF Chen, NL Benoiton

文献索引:Chen,F.M.F.; Benoiton,N.L. Journal of Organic Chemistry, 1979 , vol. 44, p. 2299 - 2300

全文:HTML全文

被引用次数: 9

摘要

0-Methyl-L-serine* and O-methyl-~-threonine~~~~ are of interest for incorporating into peptides for structure-function relationship studies and in the search for useful analogues of biologically active molecules 0-Methyl-L-threonine is also an antagonist of isoleucine, inhibiting protein synthesis by ascites tumour cells." The N-tert-butyloxycarbonyl (Boc) derivative of 0-methyl-L-serine, which is useful for synthetic work, is best obtained by a five ...