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A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl) phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis

AR Mitchell, SBH Kent, M Engelhard…

文献索引:Journal of Organic Chemistry, , vol. 43, p. 2845 - 2852

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被引用次数: 320

摘要

... A preliminary evalua- tionZ4 of this resin showed properties comparable to those reported for the resin 8. The chemistry of the Pam-resins ... J. Org. ... The organic phase was dried over anhydrous magnesium sulfate and freed of solvent by rotary evaporation under reduced pressure ...