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Identification of small peptides mimicking the R2 C??terminus of Mycobacterium tuberculosis ribonucleotide reductase

DJ Ericsson, J Nurbo, D Muthas…

文献索引:Journal of Peptide Science, , vol. 16, # 3 p. 159 - 164

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被引用次数: 7

摘要

... Journal of Peptide Science. ... acylated with 9-fluoreneacetic acid, turned out to have only slightly less affinity than the corresponding Fmoc-protected tetrapeptide 5 (K D2 = 19 ± 3 µM), with a K D2 value of 29 ± 2 µM. Making the N-terminal ring system less rigid as in peptide 9 (K ...