Amino acids

Towards non-peptide ANG II AT1 receptor antagonists based on urocanic acid: rational design, synthesis and biological evaluation

G Agelis, A Resvani, MT Matsoukas, T Tselios…

文献索引：Amino Acids, , vol. 40, # 2 p. 411 - 420

全文：HTML全文

被引用次数: 6

摘要

... 6). The main amino acids participating in hydrogen bond interactions were S3.33(109), L(191), N5 ... derivatives 11a–c as potential ANG II AT1 receptor antagonists, based on urocanic acid. ... for binding in AT1 receptor antagonists (2) the smaller molecular weight and volume of our ...