Synthesis, characterization and biological activity of new cyclization products of 3-(4-substituted benzylidene)-2H-pyrido [1, 2-a] pyrimidine 2, 4-(3H)-diones

…, S Singh, AK Tiwari, K Srivastava, R Raghuvir…

文献索引：Bishnoi, Abha; Singh, Suruchi; Tiwari, Anil K; Srivastava, Krishna; Raghuvir, Ram; Tripathi, Chandrakant M Journal of Chemical Sciences, 2013 , vol. 125, # 2 p. 305 - 312

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被引用次数: 7

摘要

Abstract A method is presented for the synthesis of 4-(substituted phenyl)-3-(3-substituted phenyl) 4 H-spiro [isoxazole-5, 3′-pyrido [1, 2-a] pyrimidine]-2′, 4′-dione (3), 3-(4- substituted phenyl)-3 H-isoxazole [3, 4-d] pyrido [1, 2-a] pyrimidin-4-(3a H)-one (4) and 3-(4- substituted phenyl) 3, 3a-dihydropyrazolo [3, 4-d] pyrido [1, 2-a] pyrimidin-4-(2 H)-one (5) which consists of the conversion of 2 H-pyrido [1, 2-a] pyrimidine-2, 4 (3 H)-dione (1) to ...