1, 3-Bis (2, 4, 6-trimethylphenyl) imidazolium chloride in combination with triethylamine: an improved catalytic system for hydroacylation/reduction of activated ketones

M Sreenivasulu, KA Kumar, KS Reddy, KS Kumar…

文献索引：Sreenivasulu; Arun Kumar; Sateesh Reddy; Siva Kumar; Rajender Kumar; Chandrasekhar; Pal, Manojit Tetrahedron Letters, 2011 , vol. 52, # 6 p. 727 - 732

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被引用次数: 13

摘要

A rapid, economic, and high yielding methodology has been developed for hydroacylation/ reduction of activated ketones by using 1, 3-bis (2, 4, 6-trimethylphenyl) imidazolium chloride as a catalyst in combination with triethylamine. The reaction proceeded at an ambient temperature via generating N-heterocyclic carbene in situ that interacted with the (hetero) aryl aldehyde employed. While the reduction of ketones takes place in MeOH, the ...