A mild and selective method for the hydrolysis of esters with trimethyltin hydroxide

…, AA Estrada, M Zak, SH Lee, BS Safina

文献索引：Nicolaou; Estrada, Anthony A.; Zak, Mark; Lee, Sang Hyup; Safina, Brian S. Angewandte Chemie - International Edition, 2005 , vol. 44, # 9 p. 1378 - 1382

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被引用次数: 223

摘要

1380 2005 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www. angewandte. org Angew. Chem. Int. Ed. 2005, 44, 1378–1382 the resulting carboxylic acid group to the proximate Michaelacceptor olefin. The scope of this method was further expanded when it was discovered that Me3SnOH could cleave the Evans oxazolidinone chiral auxiliary [5](11 b) from aldol product 11 to afford carboxylic acid 11 a in good yield (Table 2, entry 7). The ...