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Efficient Synthesis of 2, 4, 5-Triaryl-1H-Imidazoles from Aromatic Aldehydes with HMDS Catalyzed by N-Bromosaccharin (NBSa)

A Sedrpoushan, Z Joshani…

文献索引:Sedrpoushan, Alireza; Joshani, Zinab; Fatollahi, Leila Letters in Organic Chemistry, 2014 , vol. 11, # 4 p. 287 - 292

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摘要

A one-pot efficient procedure for the synthesis of 2, 4, 5-triaryl-1H-imidazole derivatives by the reactions of hexamethyldisilazane and arylaldehydes in the presence of N- bromosaccharin (NBSa) is studied. This new method offers several advantages, such as excellent yields, easy workup, short reaction times, and simple procedure.