Organometallics

Mechanistic Investigations of Cu-Catalyzed Fluorination of Diaryliodonium Salts: Elaborating the CuI/CuIII Manifold in Copper Catalysis

N Ichiishi, AJ Canty, BF Yates, MS Sanford

文献索引：Ichiishi, Naoko; Canty, Allan J.; Yates, Brian F.; Sanford, Melanie S. Organic Letters, 2013 , vol. 15, # 19 p. 5134 - 5137

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被引用次数: 18

摘要

A combination of experimental and density functional theory (DFT) investigations suggests that the Cu-catalyzed fluorination of unsymmetrical diaryliodonium salts with general structure [Mes (Ar) I]+ in N, N′-dimethylformamide proceeds through a CuI/CuIII catalytic cycle. A low concentration of fluoride relative to combined iodonium reagent plus copper ensures that [Mes (Ar) I]+ is available as the reactive species for oxidative “Ar+” transfer to ...