Synthesis and structure of biologically active ferrocenylalkyl polyfluoro benzimidazoles

…, VI Boev, YS Nekrasov, MM Ilyin, VA Davankov…

文献索引：Snegur, Lubov' V.; Boev, Victor I.; Nekrasov, Yury S.; Ilyin, Mikhail M.; Davankov, Vadim A.; Starikova, Zoya A.; Yanovsky, Alexander I.; Kolomiets, Alexey F.; Babin, Valery N. Journal of Organometallic Chemistry, 1999 , vol. 580, # 1 p. 26 - 35

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被引用次数: 33

摘要

The title compounds were synthesized in quantitative yields by interacting α-hydroxyalkyl ferrocenes with polyfluoroalkyl benzimidazoles in an aqueous-organic medium in the presence of HBF4. The resulting diastereomers and enantiomers were resolved using HPLC on silica bonded chiral stationary phases based on chiral cyclodextrins and cyclic antibiotics. The X-ray determination of molecular and crystal structure of 1- ...