Probes for narcotic receptor mediated phenomena. 41. Unusual inverse μ-agonists and potent μ-opioid antagonists by modification of the N-substituent in …

K Cheng, YS Lee, RB Rothman…

文献索引：Journal of Medicinal Chemistry, , vol. 54, # 4 p. 957 - 969

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被引用次数: 12

摘要

... Journal of Medicinal Chemistry. ... Chemistry The enantiomeric starting materials, 1S,5R-(−)-5-(3- methoxyphenyl)-2-azabicyclo[3.3.1]nonane ((−)-1) and 1R,5S-(+)-5-(3-methoxyphenyl)-2- azabicyclo-[3.3.1]nonane ((+)-1) were prepared as previously described.(4) Reaction of ...