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Azacycloalkanes. XXVII. Synthesis and antianginal activity of nonachlazine stereoisomers

…, AM Likhosherstov, TV Morozova, AP Skoldinov…

文献索引:Nazarova, L. S.; Rozonov, Yu. B.; Likhosherstov, A. M.; Morozova, T. V.; Skoldinov, A. P.; et al. Pharmaceutical Chemistry Journal, 1984 , vol. 18, # 12 p. 811 - 815 Khimiko-Farmatsevticheskii Zhurnal, 1984 , vol. 18, # 12 p. 1445 - 1448

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被引用次数: 3

摘要

It is seen from Table 1 that the stereoisomers of the intermediate and final compounds are close in absolute size and opposite in sign for the value of the specific rotation. Furthermore, the constants of diketopiperazine L-(V) synthesized by the proposed scheme agree well with the constants of this substance given in the literature and obtained in [i, 8] by other means. It is necessary to consider the possibility of racemization at the stage of reducing ...