Preparation of Boc-protected cinnamyl-type alcohols: A comparison of the Suzuki-Miyaura coupling, cross-metathesis, and Horner-Wadsworth-Emmons approaches …
…, AV Malkov, P Kočovský
文献索引:Stambasky, Jan; Malkov, Andrei V.; Kocovsky, Pavel Collection of Czechoslovak Chemical Communications, 2008 , vol. 73, # 5 p. 705 - 732
Abstract Three synthetic strategies for the construction of tert-butyl (E)-3-arylprop-2-en-1-ol carbonates are described. Complementary approaches employing Suzuki-Miyaura coupling and cross-metathesis reaction gave moderate yields of the title compounds in one-step, both methods are suitable for high-throughput and parallel chemistry. A detailed investigation into the Suzuki-Miyaura coupling reaction is provided along with the studies on the synthesis ...