前往化源商城

Tetrahedron

Regioselective synthesis of β-and γ-thujaplicins

MG Soung, M Matsui, T Kitahara

文献索引:Soung, Min-Gyu; Matsui, Masanao; Kitahara, Takeshi Tetrahedron, 2000 , vol. 56, # 39 p. 7741 - 7745

全文:HTML全文

被引用次数: 8

摘要

β-Thujaplicin (hinokitiol) 1 and γ-thujaplicin 2, as the first naturally occurring monocyclic tropolone, were regioselectively synthesized from (R)-(+)-limonene, by using different dienyl silyl ether intermediates, 7 and 10, in 18% overall yield via 11 steps and 22% overall yield via 10 steps, respectively.