Applications of high-temperature aqueous media for synthetic organic reactions

J An, L Bagnell, T Cablewski, CR Strauss…

文献索引：An, Jingyi; Bagnell, Laurence; Cablewski, Teresa; Strauss, Christopher R.; Trainor, Robert W. Journal of Organic Chemistry, 1997 , vol. 62, # 8 p. 2505 - 2511

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被引用次数: 258

摘要

Preparative organic synthesis was investigated in aqueous media at temperatures up to 300° C. Experiments were conducted with a recently disclosed pressurized microwave batch reactor (MBR) or in conventionally heated autoclaves. Thirty-six examples are presented. Among these, methods were developed for a Fischer synthesis, an intramolecular aldol condensation that was scaled up, decarboxylation of indole-2-carboxylic acid, Rupe ...