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Synthesis of deuterium-labeled azo dyes of the sudan family

…, L Di Donna, L Maiuolo, F Mazzotti, G Sindona

文献索引:De Nino, Antonio; Di Donna, Leonardo; Maiuolo, Loredana; Mazzotti, Fabio; Sindona, Giovanni Synthesis, 2008 , # 3 p. 459 - 463

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被引用次数: 5

摘要

Abstract Carcinogenic amines are formed in vivo during the metabolism of Sudan azo dyes. The identification and assay of these polluting agents requires the availability of deuterated analogues. Accordingly, two series of derivatives labeled on the phenylazo and naphthol moieties were synthesized. The new compounds were obtained in satisfactory chemical yields and with an excellent degree of labeling. The structures were confirmed by 1 H ...