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Design, synthesis, and structure-activity relationships of a series of 3-[2-(1-benzylpiperidin-4-yl) ethylamino] pyridazine derivatives as acetylcholinesterase inhibitors

JM Contreras, I Parrot, W Sippl, YM Rival…

文献索引:Journal of Medicinal Chemistry, , vol. 44, # 17 p. 2707 - 2718

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被引用次数: 104

摘要

... Journal of Medicinal Chemistry. ... Chemistry. The 3-[2-(1-benzylpiperidin-4-yl) ethylamino]pyridazines 4a−k (Tables 1, 2, and 3) were synthesized according to Scheme 1. Condensation of the iminochlorides 3 with the ...