Generation of monospecific nanomolar tyrosine kinase inhibitors via a chemical genetic approach

AC Bishop, C Kung, K Shah, L Witucki…

文献索引：Journal of the American Chemical Society, , vol. 121, # 4 p. 627 - 631

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被引用次数: 137

摘要

... Journal of the ... 1999, 121 (4), pp 627–631. DOI: 10.1021/ja983267v. Publication Date (Web): January 14, 1999. Copyright © 1999 American Chemical Society. ... Src family kinase inhibitor 4-amino-1-tert-butyl-3-phenylpyrazolo[3,4-d]pyrimidine (1, Figure 1a) as a chemical hook to ...